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KMID : 1152420220280010031
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Advances in Pediatric Surgery
2022 Volume.28 No. 1 p.31 ~ p.36
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Sirolimus Treatment of Refractory Infantile Hemangiomatosis With Brain Involvement
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Pak Shin-Jeong
Kim Dae-Yeon
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Abstract
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Infantile hemangiomas are the most common vascular tumors of infants and are characterized by abnormal proliferation of endothelial cells and aberrant blood vessel architecture. The drug Sirolimus has been explored as a new therapeutic option in the management of vascular anomalies that do not respond to conventional treatments. This report presents a case of refractory multiple infantile hemangiomatosis with brain involvement that was successfully treated with sirolimus.
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KEYWORD
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Hemangioma, Vascular malformations, Sirolimus, Rapamycin, Brain
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